产品货号:
Z11651
中文名称:
BAP31/BCAP31抗体
英文名称:
Anti-BAP31/BCAP31 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BAP31/BCAP31 Antibody |
指标别名 | 6C6 AG;BAP31;BCAP31;CDM;DXS1357E;p28;Protein CDM |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC |
基因名称 | BCAP31 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Anti-BAP31 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human BAP31.The immunogen is located within the last 50 amino acids of BAP31. |
计算分子量 | 28kDa |
成分 | BAP31 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | BAP31 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family.These two proteins are highly homologous and can form homo- and heterodimers.Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18.It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail,possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria.Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis.The p20 fragment of Bap31,when expressed ectopicially,is also a potent inducer cell death. |
Uniprot ID | P51572 |
基因名全称 | B-cell receptor-associated protein 31 |
蛋白名全称 | B-cell receptor-associated protein 31 |
推荐稀释比 | WB:0.5~2μg/mL;IHC:2μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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